Archives of Medicine and Health Sciences

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 2  |  Issue : 1  |  Page : 5--7

Antianxiety effect of ethanolic extract of leaves of Moringa oleifera in Swiss albino mice


Shankar K. Bhat, Anu Elizabeth Joy 
 Department of Physiology, Yenepoya Medical College, Mangalore, Karnataka, India

Correspondence Address:
Anu Elizabeth Joy
Department of Physiology, Yenepoya Medical College, Yenepoya University, Deralakatte, Mangalore - 575 018, Karnataka
India

Background: Anxiety disorder is one of the most common mental ailments exhibited by humans. It can cause considerable distress and debility. Anxiety is portrayed as a frame of mind concerned about future in association with preparation for possible, upcoming undesirable happenings. The present treatment for the disorder is having a lot of side-effects. An agent with good therapeutic effect and less side-effects is needed for the treatment of anxiety. Objectives: To investigate the anxiolytic activity of ethanolic extract of Moringa oleifera leaves in Swiss albino mice. Materials and Methods: The ethanolic extract of leaves of Moringa oleifera (200 mg/kg, i.p) was studied for its anxiolytic effect on Swiss albino mice by using Elevated Plus Maze (EPM) and Light Dark Arena (LDA) test. Results: The ethanolic extract of the leaves of Moringa oleifera (200 mg/kg, i.p) demonstrated significant (P < 0.001) anxiolytic activity in EPM and LDA models of anxiety. Conclusion: The data suggests that the ethanolic extract of Moringa oleifera leaves may have produced its anxiolytic effects via multiple mechanisms.


How to cite this article:
Bhat SK, Joy AE. Antianxiety effect of ethanolic extract of leaves of Moringa oleifera in Swiss albino mice.Arch Med Health Sci 2014;2:5-7


How to cite this URL:
Bhat SK, Joy AE. Antianxiety effect of ethanolic extract of leaves of Moringa oleifera in Swiss albino mice. Arch Med Health Sci [serial online] 2014 [cited 2020 May 31 ];2:5-7
Available from: http://www.amhsjournal.org/article.asp?issn=2321-4848;year=2014;volume=2;issue=1;spage=5;epage=7;aulast=Bhat;type=0