Archives of Medicine and Health Sciences

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 6  |  Issue : 2  |  Page : 218--222

First day serum bilirubin level, as predictor of significant hyperbilirubinemia in neonates


Jehangir Bhat Allam, Santosh Kumar, Rajesh Kurmi, Roshan Ara, Amit Mittal Kumar 
 Department of Paediatrics, Kurji Holy Family Hospital, Patna, Bihar, India

Correspondence Address:
Dr. Jehangir Bhat Allam
Department of Paediatrics, Kurji Holy Family Hospital, Patna, Bihar
India

Background: Age-specific (24 ± 6 h) predictive value of total serum bilirubin (TSB) ≤6 mg/dl in developing significant hyperbilirubinemia in infants. Materials and Methods: A prospective observational study on 200 term neonates having birth weight ≥2500 g and gestational age ≥37 weeks. Blood was collected from the venous site. The blood sample of all infants was sent for grouping and TSB estimation. Babies were clinically examined every day for jaundice. Whenever jaundice was clinically noticed to be >10 mg/dl, bilirubin estimation was repeated immediately and then every day until 5 days of age, and the highest reading was recorded as the peak TSB. Results: Significant hyperbilirubinemia (>17 mg/dl) was present in 13% of cases. At 24 ± 6 h, TSB >6 mg/dl was present in 47 cases and 26 of these developed hyperbilirubinemia (≥17 mg/dl), and TSB ≤6 mg/dl was present in 153 cases and two of them developed significant hyperbilirubinemia. The incidence of hyperbilirubinemia in babies whose mothers received oxytocin and those whose mothers did not receive oxytocin was 19.6% and 8.2%, respectively. The difference was highly significant. The mean values of TSB at 24 ± 6 h in oxytocin used and oxytocin not used groups were 3.94 ± 2.15 mg/dl and 3.36 ± 1.91 mg/dl, respectively, the difference was statistically significant; however, the mean values of peak TSB in oxytocin used and not used groups were 12.78 ± 4.28 mg/dl and 12.03 ± 3.42 mg/dl, respectively, which were statistically not significant. Conclusion: The incidence of significant hyperbilirubinemia in healthy babies is 13%. The use of oxytocin increased its incidence. TSB at 24 ± 6 h ≤6 mg/dl has a high predictive value in identifying those infants who are unlikely to develop subsequent hyperbilirubinemia. This study, thus, will help to discharge healthy term infants with TSB on 2nd day ≤6 mg/dl.


How to cite this article:
Allam JB, Kumar S, Kurmi R, Ara R, Kumar AM. First day serum bilirubin level, as predictor of significant hyperbilirubinemia in neonates.Arch Med Health Sci 2018;6:218-222


How to cite this URL:
Allam JB, Kumar S, Kurmi R, Ara R, Kumar AM. First day serum bilirubin level, as predictor of significant hyperbilirubinemia in neonates. Arch Med Health Sci [serial online] 2018 [cited 2019 Aug 25 ];6:218-222
Available from: http://www.amhsjournal.org/article.asp?issn=2321-4848;year=2018;volume=6;issue=2;spage=218;epage=222;aulast=Allam;type=0