Archives of Medicine and Health Sciences

CASE REPORT
Year
: 2019  |  Volume : 7  |  Issue : 2  |  Page : 248--250

Swyer syndrome (46XY pure gonadal dysgenesis) presenting with dysgerminoma


M Banyameen Iqbal1, Iqra Mushtaq2, Tushar Kambale1, Indranil Dey1 
1 Department of Pathology, Dr. D.Y. Patil Medical College, Hospital and Research Center, Pune, Maharashtra, India
2 Department of Ophthalmology, Dr. D.Y. Patil Medical College, Hospital and Research Center, Pune, Maharashtra, India

Correspondence Address:
Dr. M Banyameen Iqbal
Department of Pathology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, Maharashtra
India

Dysgerminoma is the most common malignant germ cell tumor of the ovary. This malignancy can be associated with pure gonadal dysgenesis (Swyer syndrome), mixed gonadal dysgenesis, and partial gonadal dysgenesis. Dysgerminoma usually develops in phenotypic females with 46XY pure gonadal dysgenesis. This patient presented with an abdominopelvic mass. Laparotomy was done. 46XY karyotype was detected by lymphocyte culture. The patient underwent gonadectomy, and histopathological results were streak ovaries with dysgerminoma. Five percent of dysgerminomas are discovered in phenotypic female and 46XY karyotype; thus, in an adolescent with dysgerminomas and amenorrhea, karyotyping should be done.


How to cite this article:
Iqbal M B, Mushtaq I, Kambale T, Dey I. Swyer syndrome (46XY pure gonadal dysgenesis) presenting with dysgerminoma.Arch Med Health Sci 2019;7:248-250


How to cite this URL:
Iqbal M B, Mushtaq I, Kambale T, Dey I. Swyer syndrome (46XY pure gonadal dysgenesis) presenting with dysgerminoma. Arch Med Health Sci [serial online] 2019 [cited 2020 Sep 28 ];7:248-250
Available from: http://www.amhsjournal.org/article.asp?issn=2321-4848;year=2019;volume=7;issue=2;spage=248;epage=250;aulast=Iqbal;type=0