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REVIEW ARTICLE
Year : 2015  |  Volume : 3  |  Issue : 2  |  Page : 252-265

Pediatric cardiogenic shock: Current perspectives


Department of Paediatrics, Ras al-Khaimah (RAK) Medical and Health Sciences University, Al Qusaidat, Ras al-Khaimah, United Arab Emirates

Correspondence Address:
Subhranshu Sekhar Kar
Department of Paediatrics, Ras al-Khaimah (RAK) Medical and Health Sciences University, Al Qusaidat, Ras al-Khaimah
United Arab Emirates
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2321-4848.171917

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Cardiogenic shock is a pathophysiologic state where an abnormality of cardiac function is responsible for the failure of the cardiovascular system to meet the metabolic needs of the body tissues.Though it is less common than hypovolemia as the primary etiology in paediatric shock, eventually myocardial function is affected because of reduced perfusion in all forms of shock. Myocardial malfunction, in other forms of shock, is secondary to ischemia, acidosis, drugs, toxins or inflammation. Cardiogenic shock is a low output state characterized by elevated filling pressures, neurohormonal activation with the evidence of end-organ hypoperfusion. The management is challenging and consists of a combination of conventional cardio-respiratory support, vasoactive medications with correction of the anatomic cardiac defects. Treatment options like Extracorporeal membrane oxygenation and Ventricular assist devices provide a bridge to recovery, surgery or transplant. As cardiogenic shock in children carries a high risk of morbidity and mortality, emphasis should be placed on expedient management to arrest the pathophysiological cascade and avoid hypotension.This article aims to review the aetio-pathophysiological basis of pediatric cardiogenic shock, diagnostic options, recent advances in management modalities and outcome.


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